The mitigating factor that would most significantly minimize the impact of not renewing IT risk acceptances in a timely manner is having documented compensating controls over the business processes. Compensating controls are alternative controls that reduce or eliminate the risk when the primary control is not feasible or cost-effective. The other factors, such as previous approval by senior management, unchanged business environment, and small percentage of issues, do not mitigate the risk as effectively as compensating controls.
References: ISACA CISA Review Manual 27th Edition Chapter 1

A computer forensic audit is a process of collecting, preserving, analyzing, and presenting digital evidence from electronic devices in a legally admissible manner. It is most relevant in situations where data loss due to hacking of servers occurs, as it can help to identify the source, method, and extent of the attack, as well as recover the lost or damaged data. The other options are not as suitable for a computer forensic audit, as they relate to internal control issues, data quality issues, or system maintenance issues, which can be addressed by other types of audits or reviews. References: CISA Review Manual (Digital Version), Domain 4: Information Systems Operations and Business Resilience, Section 4.5 Computer Forensics1

The greatest risk associated with having most users with administrator access to an externally facing system containing sensitive data is that users can make unauthorized changes to the system or the data, which could compromise the integrity, confidentiality, and availability of the system and the data. Users can export application logs, view sensitive data, and install open-licensed software are also risks, but they are not as severe as unauthorized changes. References: ISACA CISA Review Manual 27th Edition Chapter 4

The first thing that an IS auditor should do when management responses to an in-person internal control questionnaire indicate a key internal control is no longer effective is to ascertain the existence of other compensating controls. Compensating controls are alternative controls that provide reasonable assurance of achieving the same objective as the original control. The IS auditor should verify whether there are any compensating controls in place that can mitigate the risk of the key control being ineffective, and evaluate their adequacy and effectiveness. The other options are not the first steps, because they either require more information about the compensating controls, or they are actions to be taken after identifying and assessing the compensating controls. References: CISA Review Manual (Digital Version)1, Chapter 2, Section 2.2.3