An IS auditor's review of an organization's technology relationships, interfaces, and data should focus on the organization's information security architecture. This includes analyzing the organization's security policies and procedures, as well as identifying and assessing the effectiveness of its security controls. The auditor should also review the organization's security framework to ensure that it is comprehensive and covers all areas of the enterprise architecture. Other areas such as reference architecture, infrastructure architecture, and application architecture should also be assessed, but should not be the primary focus of the review.